Level 15

There's always a chance that any antivirus/internet security software may interfere with the operation of ProSeries (or other applications, for that matter).  You may like to refer to this Intuit article for how you may need to configure your antivirus software to whitelist ProSeries:

As for which security software is best, that's sometimes a matter of perspective and it often depends on the user's technical knowledge, as some offer more finite control than others, which novices may not want to tinker with.  In terms of reliability and robustness, you may like to refer to the industry-recognized test results from AV-Test:

Still an AllStar