A couple of returns are giving you problems or are all of your returns failing to launch?  You have successfully transmitted returns previously and the problem just popped up?

 A couple of simple things to try first, if you haven't already.  Try rebooting your computer.  If that doesn't do anything, try clicking on your computer start menu, select ProSeries and then click on repair updates.

I have assumed that you have scoured those returns and nothing is showing up as pink in the forms area?