In ProConnect Tax, a sale or disposition of assets can be entered in the Dispositions (Schedule D/4797/etc. screen) or the Depreciation screen. Click on the screen you want to use below to view instructions on entering the item.
In most cases cryptocurrency or virtual currency is reported on the tax return in the same manner as property such as stock or other capital gains or losses. See Frequently Asked Questions on Virtual Currency Transactions for the IRS guidelines. If you are reporting virtual currency transactions in the 1040 return, be sure to mark the Yes box on the "At any time during 2021, did you receive, sell, exchange, or otherwise dispose of any financial interest in any virtual currency" question.