@George4Tacks 

Can we make these go away?  I checked setting/options/display but it's not in there.

You can't remove the eSignature Dashboard Tab or the Integrations Tab. To remove the Trial Balance Tab, go to the View Menu at the top, and click the item that says Trial Balance Tab.

I just get used to ignoring them.

@sjrcpa  

Ignore what ?  😉

Thank you!

In ProSeries 2021 I can not stop the tab for esignature popup-How can I stop this from popping up all the time in PS 2021?

I think many of us have developed a very useful tunnel vision to only see what we want. I makes life much easier. 

Learn to pick your fights.